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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Macrophage metalloelastase
(Homo sapiens (Human))
University Of California San Diego
Curated by
ChEMBL
Ligand
BDBM27857
(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of human recombinant MMP-12 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 30 mins prior to substrate additi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Lethal factor
(Bacillus anthracis)
Howard Hughes Medical Institute
Ligand
BDBM27857
(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
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Affinity Data
IC50: >1.00E+5nM
pH: 7.0 T: 2°C
Assay Description:
Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI