BDBM27857 1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dihydropyridine-2-carboxamide::N-hydroxypyridinone amide, 9a
SMILES On1c(cccc1=O)C(=O)NCc1ccc(cc1)-c1ccccc1
InChI Key InChIKey=DDIJQZRWMIFTHG-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 27857
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant MMP-12 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 30 mins prior to substrate additi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California San Diego
Curated by ChEMBL
University Of California San Diego
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair