BDBM27857 1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dihydropyridine-2-carboxamide::N-hydroxypyridinone amide, 9a

SMILES On1c(cccc1=O)C(=O)NCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=DDIJQZRWMIFTHG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 27857   

TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant MMP-12 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 30 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrilysin(Homo sapiens (Human))TBA
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))TBA
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails PubMed