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Found 3 of ec50 for monomerid = 281728
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM281728((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...)
Affinity DataEC50:  22nMpH: 7.5 T: 2°CAssay Description:To carry out the assay, 29 μl of enzyme solution [0-10 nM soluble guanylate cyclase (prepared according to Hönicka et al, J. Mol. Med. 77, 14-23...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM281728((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...)
Affinity DataEC50:  22nMAssay Description:Soluble guanylate cyclase (sGC) converts on stimulation GTP into cGMP and pyrophosphate (PPi). PPi is detected with the aid of the assay described be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM281728((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...)
Affinity DataEC50:  89nMAssay Description:Soluble guanylate cyclase (sGC) converts on stimulation GTP into cGMP and pyrophosphate (PPi). PPi is detected with the aid of the assay described be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent