Found 15 of ic50 for monomerid = 50056676 TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human N-terminal His-tagged TEV protease site linked ALK2 Q207D mutant (201 to 499 residues) expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK1 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK2 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of ALK3 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293T cells cotransfected with CAGA reporter encoding luciferase by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
