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Found 3 Enz. Inhib. hit(s) with Target = 'Alpha-ketoglutarate-dependent dioxygenase FTO' and Ligand = 'BDBM50328019'
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50328019(2-(3-hydroxypicolinamido)acetic acid | CHEMBL12565...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50328019(2-(3-hydroxypicolinamido)acetic acid | CHEMBL12565...)
Affinity DataIC50:  1.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50328019(2-(3-hydroxypicolinamido)acetic acid | CHEMBL12565...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incub...More data for this Ligand-Target Pair