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Found
1
Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM446331'
Target
Ataxin-1
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM446331
((3aS,8aR)-2-(1H-benzotriazole-5-carbonyl)-octahydr...)
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Affinity Data
IC50: 2nM
Assay Description:
ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
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In Depth
Details
US Patent
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