BDBM446331 (3aS,8aR)-2-(1H-benzotriazole-5-carbonyl)-octahydro-pyrrolo[3,4-d]azepine-6-carboxylic acid 2-fluoro-4-(2,2,2-trifluoro-ethoxy)-benzyl ester::US10669268, Example 1.47

SMILES Fc1cc(OCC(F)(F)F)ccc1COC(=O)N1CC[C@@H]2CN(C[C@@H]2CC1)C(=O)c1ccc2[nH]nnc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446331   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM446331((3aS,8aR)-2-(1H-benzotriazole-5-carbonyl)-octahydr...)
Affinity DataIC50:  2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent