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Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM50355099'
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355099(CHEMBL1835322)
Affinity DataIC50:  24nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355099(CHEMBL1835322)
Affinity DataIC50:  26nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed