Found 2 Enz. Inhib. hit(s) with Target = 'Serine hydroxymethyltransferase, mitochondrial' and Ligand = 'BDBM285662' TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University
US Patent
The Trustees Of Princeton University
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University
US Patent
The Trustees Of Princeton University
US Patent
Affinity DataIC50: 1nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
