Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of ic50 for UniProtKB: P15086
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586498(CHEMBL5077332)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572906(CHEMBL4854665)
Affinity DataIC50: <10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572907(CHEMBL4850503)
Affinity DataIC50: <10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572908(CHEMBL4872977)
Affinity DataIC50: <10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572909(CHEMBL4856985)
Affinity DataIC50: <10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572910(CHEMBL4861007)
Affinity DataIC50: <10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572911(CHEMBL4852677)
Affinity DataIC50: <10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50:  17nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50:  17nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586497(CHEMBL5076974)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586487(CHEMBL5087497)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586500(CHEMBL5078591)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586486(CHEMBL5082067)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586499(CHEMBL5092743)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586495(CHEMBL5084119)
Affinity DataIC50:  61nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586494(CHEMBL5092187)
Affinity DataIC50:  84nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586488(CHEMBL5084812)
Affinity DataIC50:  89nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586485(CHEMBL5077723)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50:  280nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586493(CHEMBL5083998)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586489(CHEMBL5094039)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586483(CHEMBL5091512)
Affinity DataIC50:  790nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586492(CHEMBL5076504)
Affinity DataIC50:  970nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572911(CHEMBL4852677)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572907(CHEMBL4850503)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572909(CHEMBL4856985)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572910(CHEMBL4861007)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572908(CHEMBL4872977)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50572906(CHEMBL4854665)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586491(CHEMBL5081806)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586490(CHEMBL5083959)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586484(CHEMBL5092569)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586496(CHEMBL5072742)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586481(CHEMBL5091996)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586480(CHEMBL5094929)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586482(CHEMBL5078612)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50586479(CHEMBL5081407)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611052(CHEMBL5270921)
Affinity DataIC50:  8.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611059(CHEMBL5286034)
Affinity DataIC50:  2.80E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611060(CHEMBL5288865)
Affinity DataIC50:  5.17E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611055(CHEMBL5282296)
Affinity DataIC50:  6.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611056(CHEMBL5276433)
Affinity DataIC50:  9.80E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611054(CHEMBL5281978)
Affinity DataIC50: >2.50E+5nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails PDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611057(CHEMBL5286336)
Affinity DataIC50: >2.50E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50611053(CHEMBL5281651)
Affinity DataIC50:  3.32E+5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetN6-adenosine-methyltransferase catalytic subunit(Homo sapiens)
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataIC50:  4.95E+5nMMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)