Compile Data Set for Download or QSAR
maximum 50k data
Found 2450 of ic50 for UniProtKB: Q86V86
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50:  0.00900nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM106870(US8592455, 70)
Affinity DataIC50:  0.00900nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM192574(US9187486, 37 | US9187486, 39 | US9187486, 60)
Affinity DataIC50:  0.0270nMAssay Description:Inhibition of Pim3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0890nMAssay Description:Inhibition of human PIM3 using RSRHSSYPAGT as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0980nMAssay Description:Inhibition of human PIM3 using RSRHSSYPAGT as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.121nMAssay Description:Inhibition of human PIM3 using RSRHSSYPAGT as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151870(US8987457, 64)
Affinity DataIC50:  0.220nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151941(US8987457, 135)
Affinity DataIC50:  0.260nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM224899(US9321756, 152)
Affinity DataIC50:  0.307nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151888(US8987457, 82)
Affinity DataIC50:  0.320nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM224980(US9321756, 247)
Affinity DataIC50:  0.346nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151972(US8987457, 166)
Affinity DataIC50:  0.360nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151952(US8987457, 146)
Affinity DataIC50:  0.390nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50232778(CHEMBL4062256)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM3 (1 to 326 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151875(US8987457, 69)
Affinity DataIC50:  0.400nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50061168(CHEMBL3393706)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length recombinant Pim-3 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151980(US8987457, 174)
Affinity DataIC50:  0.410nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM224903(US9321756, 155)
Affinity DataIC50:  0.425nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151878(US8987457, 72)
Affinity DataIC50:  0.430nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM224998(US9321756, 264 | US9321756, 265)
Affinity DataIC50:  0.435nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151867(US8987457, 61)
Affinity DataIC50:  0.490nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151864(US8987457, 58)
Affinity DataIC50:  0.490nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM225077(US9321756, 46)
Affinity DataIC50:  0.498nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151877(US8987457, 71)
Affinity DataIC50:  0.540nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151954(US8987457, 148)
Affinity DataIC50:  0.550nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)
Affinity DataIC50:  0.570nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM225042(US9321756, 4)
Affinity DataIC50:  0.586nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151839(US8987457, 33)
Affinity DataIC50:  0.610nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151999(US8987457, 193)
Affinity DataIC50:  0.620nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151862(US8987457, 56)
Affinity DataIC50:  0.620nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM225051(US9321756, 13)
Affinity DataIC50:  0.625nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151889(US8987457, 83)
Affinity DataIC50:  0.640nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151811(US8987457, 5)
Affinity DataIC50:  0.640nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM224841(US9321756, 100)
Affinity DataIC50:  0.668nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151893(US8987457, 87)
Affinity DataIC50:  0.680nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50061178(CHEMBL3393704)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of full length recombinant Pim-3 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50061199(CHEMBL3393697)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of full length recombinant Pim-3 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151872(US8987457, 66)
Affinity DataIC50:  0.730nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM224873(US9321756, 128)
Affinity DataIC50:  0.734nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151887(US8987457, 81)
Affinity DataIC50:  0.740nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151960(US8987457, 154)
Affinity DataIC50:  0.740nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151989(US8987457, 183)
Affinity DataIC50:  0.75nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151965(US8987457, 159)
Affinity DataIC50:  0.75nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151967(US8987457, 161)
Affinity DataIC50:  0.760nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50061613(CHEMBL3394164 | US9321756, 17)
Affinity DataIC50:  0.763nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151886(US8987457, 80)
Affinity DataIC50:  0.790nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of N-terminal 6-His tagged human recombinant PIM3 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PIM3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50499276(CHEMBL3735861)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM151962(US8987457, 156)
Affinity DataIC50:  0.800nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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