Compile Data Set for Download or QSAR
maximum 50k data
Found 224 of ki data for polymerid = 49000618,50001722
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060627((S)-2-Amino-3-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyr...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053067((2S,3S,4S)-3-Carboxymethyl-4-(1-phenyl-vinyl)-pyrr...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053071((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-3-methyl...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053075((2S,3S,4S)-4-(1-Biphenyl-3-yl-vinyl)-3-carboxymeth...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053083((2S,3S,4S)-3-Carboxymethyl-4-(1-m-tolyl-vinyl)-pyr...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053080((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,4-dimethyl-phen...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053088((2S,3S,4S)-3-Carboxymethyl-4-(1-p-tolyl-vinyl)-pyr...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053087((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-phenyl)-...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053064((2S,3S,4S)-4-[1-(4-Butoxy-phenyl)-vinyl]-3-carboxy...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060630((S)-2-Amino-3-(6-bromo-3,5-dioxo-4,5-dihydro-3H-[1...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053063((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methoxy-phenyl)...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053068((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-isopropenyl-phe...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053059((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-propyl-phenyl)-...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053061((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-chloro-phenyl)-...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053073((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-methoxy-phenyl)...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053082((2S,3S,4S)-4-[1-(4-Butyl-phenyl)-vinyl]-3-carboxym...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50252103((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...)
Affinity DataKi:  6.04nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053065((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenethyloxy-ph...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053089((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-ethyl-phenyl)-v...)
Affinity DataKi:  7.70nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  8nMAssay Description:Ability of the compound to bind to Ionotropic glutamate receptor kainate (kainate 2) was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053070((2S,3S,4S)-3-Carboxymethyl-4-{1-[4-(1-methylene-pr...)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053076((2S,3S,4S)-4-(1-Biphenyl-4-yl-vinyl)-3-carboxymeth...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060636((S)-2-Amino-3-(5-bromo-2,4-dioxo-3,4-dihydro-2H-py...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053062((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,5-dimethyl-phen...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053074((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenoxy-phenyl)...)
Affinity DataKi:  11.9nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053077((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-phenethyloxy-ph...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50031704((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053060((2S,3S,4S)-4-[1-(4-tert-Butyl-phenyl)-vinyl]-3-car...)
Affinity DataKi:  18.5nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50166288((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060629((S)-2-Amino-3-(6-iodo-3,5-dioxo-4,5-dihydro-3H-[1,...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053079((2S,3S,4S)-4-[1-(3-Butoxy-phenyl)-vinyl]-3-carboxy...)
Affinity DataKi:  23.3nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060628((S)-2-Amino-3-(6-chloro-3,5-dioxo-4,5-dihydro-3H-[...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50211399((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM86754(LY 466195 | LY-466195)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50060632((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  80nMAssay Description:Binding affinity of compound was determined against Glutamate receptor (KA2) using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50166287((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...)
Affinity DataKi: >100nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50166285((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...)
Affinity DataKi: >100nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50166286((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...)
Affinity DataKi: >100nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50252051((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053066((2S,3S,4S)-3-Carboxymethyl-4-{1-[4-(5-phenyl-penty...)
Affinity DataKi:  126nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM17660((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  177nMAssay Description:Displacement of [3H]kainate from human Ionotropic glutamate receptor ionotropic kainate 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053078((2S,3S,4S)-3-Carboxymethyl-4-{1-[3-(3,3-diphenyl-p...)
Affinity DataKi:  210nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50053069((2S,3S,4R)-3-Carboxymethyl-4-(1-phenyl-vinyl)-pyrr...)
Affinity DataKi:  230nMAssay Description:Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]SYM2081 from rat iGluR6 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataKi:  331nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK2(VCR) receptor expressed in sf9 cells by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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