Found 461 Enz. Inhib. hit(s) with Target = 'Protein-tyrosine kinase 6' 
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 980nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 7.80nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 2.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 6.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 uM ATP.). Reaction condition...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 uM ATP.). Reaction condition...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BRK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BRK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding affinity to BRKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to BRKMore data for this Ligand-Target Pair
Affinity DataKd: 2.30E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: <7nMAssay Description:Inhibition of phosphorylated SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.30E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BRKMore data for this Ligand-Target Pair
Affinity DataIC50: 5.81E+4nMAssay Description:Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.24E+4nMAssay Description:Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assayMore data for this Ligand-Target Pair
