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Found 8 Enz. Inhib. hit(s) with all data for entry = 3184
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393615(US09969700, 173)
Affinity DataIC50:  64nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393614(US09969700, 48)
Affinity DataIC50:  430nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393617(US09969700, 197)
Affinity DataIC50:  440nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393612(5-[4-[(2-Chlorophenylacetyl)amino]phenyl]-1H-napht...)
Affinity DataIC50:  540nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393616(US09969700, 196)
Affinity DataIC50:  970nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393613(US09969700, 20)
Affinity DataIC50:  1.20E+3nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM393619(5-[4-(2-Iodobenzoyl)aminophenyl]-1,2,3,4,8,9,10,11...)
Affinity DataIC50:  1.80E+3nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 4(Homo sapiens (Human))
Nippon Chemiphar

US Patent
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataIC50:  4.00E+3nMAssay Description:The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...More data for this Ligand-Target Pair
In DepthDetails US Patent