Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50019135
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202179(2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-thiox...)
Affinity DataIC50:  900nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202169((R)-2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-t...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202164(2-(5-(3-(3,4-dichlorophenoxy)benzylidene)-4-oxo-2-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202174((R)-2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-t...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202149(5-(3,5-bis(benzyloxy)benzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202167((R)-2-(5-(3-(3,4-dichlorophenoxy)benzylidene)-4-ox...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202173(5-(3-(4-tert-butylphenoxy)benzylidene)-2-thioxothi...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202166(5-(3,4-bis(benzyloxy)benzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202180((R)-2-(5-(3-(3,4-dichlorophenoxy)benzylidene)-4-ox...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202163((E)-5-(3-(3,5-dichlorophenoxy)benzylidene)-2-thiox...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202170((E)-5-(3-(3,4-dichlorophenoxy)benzylidene)-2-thiox...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202158(5-(4-(4-chlorobenzyloxy)-3-methoxybenzylidene)-2-t...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202175(5-(3-(4-chlorophenoxy)benzylidene)-2-thioxothiazol...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202177(5-(3-(4-(trifluoromethyl)phenoxy)benzylidene)-2-th...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202151(3-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-thiox...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202157(2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-thiox...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202168(5-(3-(4-tert-butylphenoxy)benzylidene)thiazolidine...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202161(5-(3-(3,5-dichlorophenoxy)benzylidene)thiazolidine...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202162(5-(3-(3,4-dichlorophenoxy)benzylidene)thiazolidine...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202178(2-(5-(3-(3,4-dichlorophenoxy)benzylidene)-4-oxo-2-...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202145(5-(4-(4-methoxybenzyloxy)-3-methoxybenzylidene)-2-...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202165(5-(3-(p-tolyloxy)benzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202153(5-(3-(4-methoxyphenoxy)benzylidene)-2-thioxothiazo...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202152(5-(3-(benzyloxy)benzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202147(5-(3-phenoxybenzylidene)-2-thioxothiazolidin-4-one...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202146(5-(4-(benzyloxy)-3-methoxybenzylidene)-2-thioxothi...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202155(5-(3-(4-chlorophenoxy)benzylidene)-1-methylimidazo...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202150(5-(3-(4-chlorophenoxy)benzylidene)thiazolidine-2,4...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202156(5-(3-(3,5-dichlorophenoxy)benzylidene)imidazolidin...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202160(5-(3-(4-chlorophenoxy)benzylidene)imidazolidine-2,...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202159(5-(3-(4-tert-butylphenoxy)benzylidene)imidazolidin...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202171(5-(3,4-bis(benzyloxy)benzylidene)-3-phenethyl-2-th...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202148(5-(3,4-bis(benzyloxy)benzylidene)-3-phenyl-2-thiox...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202154(5-(3,4-bis(benzyloxy)benzylidene)-3-methyl-2-thiox...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202176(5-(3,4-bis(benzyloxy)benzylidene)-3-ethyl-2-thioxo...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202172(5-(3,4-bis(benzyloxy)benzylidene)-3-benzyl-2-thiox...)
Affinity DataIC50: >6.70E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed