Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50019188
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202421(3,3'-difluoro-4'-((R)-1-{[1-(3,3,3-trifluoro-propi...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202429(CHEMBL414962 | methyl 4'-{(1R)-1-[({1-[(difluoroac...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202412(3-Chloro-3'-fluoro-4'-((R)-1-{[1-(2,2,2-trifluoro-...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202409(CHEMBL218605 | N-{(1R)-1-[3,3'-difluoro-2'-(3-meth...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202422(CHEMBL424919 | methyl 4'-{[({1-[(dichloroacetyl)am...)
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202418(CHEMBL374580 | methyl 3,3'-difluoro-4'-{(1R)-1-[({...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202416(CHEMBL220657 | N-{(1R)-1-[3,3'-difluoro-2'-(2-meth...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202425(CHEMBL426561 | N-{(1R)-1-[3'-chloro-3-fluoro-2'-(2...)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202431(CHEMBL220371 | methyl 4'-((1R)-1-{[(1-{[chloro(dif...)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202426(3,3'-difluoro-4'-({[1-(3,3,3-trifluoro-propionylam...)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202427(CHEMBL221288 | methyl 4'-[(1R)-1-({[1-(acetylamino...)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202414(CHEMBL218553 | ethyl 3-chloro-3'-fluoro-4'-{(1R)-1...)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202423(CHEMBL221695 | N-{(1R)-1-[3,3'-difluoro-2'-(triflu...)
Affinity DataKi:  1.44nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202419(3,3'-Difluoro-4'-({[1-(2,2,2-trifluoro-acetylamino...)
Affinity DataKi:  1.47nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202408(CHEMBL373803 | methyl 3,3'-difluoro-4'-{(1R)-1-[({...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202408(CHEMBL373803 | methyl 3,3'-difluoro-4'-{(1R)-1-[({...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202428(CHEMBL222159 | N-[(1R)-1-(3'-chloro-3-fluoro-2'-pr...)
Affinity DataKi:  1.95nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202412(3-Chloro-3'-fluoro-4'-((R)-1-{[1-(2,2,2-trifluoro-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to rhesus monkey bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202411(CHEMBL218267 | methyl 4'-({[(1-{[chloro(difluoro)a...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202410(CHEMBL218552 | methyl 4'-({[(1-{[chloro(fluoro)ace...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202420(CHEMBL219309 | methyl 3,3'-difluoro-4'-{[({1-[(2,2...)
Affinity DataKi:  2.95nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202412(3-Chloro-3'-fluoro-4'-((R)-1-{[1-(2,2,2-trifluoro-...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity to rabbit bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202424(CHEMBL218319 | methyl 3'-fluoro-4'-{(1R)-1-[({1-[(...)
Affinity DataKi:  10.3nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202415(CHEMBL387331 | methyl 4'-[({[1-(acetylamino)cyclop...)
Affinity DataKi:  11.6nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202413(CHEMBL384893 | methyl 4'-{[({1-[(difluoroacetyl)am...)
Affinity DataKi:  13.5nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50411233(CHEMBL2096845)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202430(CHEMBL220978 | N-{(1R)-1-[3,3'-difluoro-2'-(1-meth...)
Affinity DataKi:  62.5nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202417(CHEMBL219164 | methyl 4'-{[({1-[(2,2-dichloropropa...)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202412(3-Chloro-3'-fluoro-4'-((R)-1-{[1-(2,2,2-trifluoro-...)
Affinity DataKi:  1.65E+3nMAssay Description:Binding affinity to rat bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202416(CHEMBL220657 | N-{(1R)-1-[3,3'-difluoro-2'-(2-meth...)
Affinity DataIC50:  0.650nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202409(CHEMBL218605 | N-{(1R)-1-[3,3'-difluoro-2'-(3-meth...)
Affinity DataIC50:  0.890nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202412(3-Chloro-3'-fluoro-4'-((R)-1-{[1-(2,2,2-trifluoro-...)
Affinity DataIC50:  1.52nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202418(CHEMBL374580 | methyl 3,3'-difluoro-4'-{(1R)-1-[({...)
Affinity DataIC50:  1.90nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202423(CHEMBL221695 | N-{(1R)-1-[3,3'-difluoro-2'-(triflu...)
Affinity DataIC50:  7.30nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202414(CHEMBL218553 | ethyl 3-chloro-3'-fluoro-4'-{(1R)-1...)
Affinity DataIC50:  9.10nMAssay Description:Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202417(CHEMBL219164 | methyl 4'-{[({1-[(2,2-dichloropropa...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202422(CHEMBL424919 | methyl 4'-{[({1-[(dichloroacetyl)am...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202415(CHEMBL387331 | methyl 4'-[({[1-(acetylamino)cyclop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202420(CHEMBL219309 | methyl 3,3'-difluoro-4'-{[({1-[(2,2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202413(CHEMBL384893 | methyl 4'-{[({1-[(difluoroacetyl)am...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202410(CHEMBL218552 | methyl 4'-({[(1-{[chloro(fluoro)ace...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202419(3,3'-Difluoro-4'-({[1-(2,2,2-trifluoro-acetylamino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202411(CHEMBL218267 | methyl 4'-({[(1-{[chloro(difluoro)a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202426(3,3'-difluoro-4'-({[1-(3,3,3-trifluoro-propionylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed