Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50030692
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300187(CHEMBL573106 | N-[4-(1-BENZYLCARBAMOYL-2-METHYL-PR...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300171(CHEMBL572692 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300172(CHEMBL572773 | N-[(1S,2S,4R)-5-benzyloxy-1-(3,5-di...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300173(CHEMBL572772 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300176(2-Ethyl-6-methyl-7,7-dioxo-6,7,8,9-tetrahydro-7lam...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300175(CHEMBL583703 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300174(CHEMBL583699 | N-[1S-(3,5-difluoro-phenoxymethyl)-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300177(CHEMBL583303 | N-[1S-(3,5-difluoro-phenoxymethyl)-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300178(CHEMBL583697 | N-[(1S,2S,4R)-5-cyclopropylmethoxy-...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300179(CHEMBL583700 | N-[(1S,2S,4R)-5-allyloxy-1-(3,5-dif...)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300180(CHEMBL573378 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300186(CHEMBL583302 | N-[5-benzylamino-1S-(3,5-difluoro-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300182(CHEMBL572771 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300185(CHEMBL583915 | N-[5-benzylamino-1S-(3,5-difluoro-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300181(CHEMBL583496 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300184(CHEMBL583702 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300183(CHEMBL583701 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed