BDBM50300182 CHEMBL572771::N-[(1S,2S,4R)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4,5-dimethoxy-pentyl]-5-(methanesulfonyl-methyl-amino)-N'-(1R-phenylethyl)-isophthalamide

SMILES COC[C@@H](C[C@H](O)[C@H](COc1cc(F)cc(F)c1)NC(=O)c1cc(cc(c1)C(=O)N[C@H](C)c1ccccc1)N(C)S(C)(=O)=O)OC

InChI Key InChIKey=FMJKXKPPBJGTCN-JVEPGKPJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300182   

TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300182(CHEMBL572771 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed