Reaction Details Report a problem with these data
Target
Histone acetyltransferase KAT2B [719-832]
Ligand
BDBM311415
Substrate
n/a
Meas. Tech.
PCAF AlphaLisa Binding Assay
IC50
240±n/a nM
Citation
 Albrecht, BK; Cote, A; Crawford, T; Duplessis, M; Good, AC; LeBlanc, Y; Magnuson, S; Nasveschuk, CG; Pastor, R; Romero, AF; Taylor, AM Therapeutic compounds and uses thereof US Patent  US10155764 Publication Date 12/18/2018 
Target
Name:
Histone acetyltransferase KAT2B [719-832]
Synonyms:
KAT2B | KAT2B_HUMAN | PCAF | PCAF (aa 719-832)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13623.13
Organism:
Homo sapiens (Human)
Description:
Q92831[719-832]
Residue:
114
Sequence:
SKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
  
Inhibitor
Name:
BDBM311415
Synonyms:
US10155764, Example 10
Type:
Small organic molecule
Emp. Form.:
C17H21N5O
Mol. Mass.:
311.3815
SMILES:
CN(C)C(CNc1nn(C)c(=O)c2[nH]ccc12)c1ccccc1
Structure:
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