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Target
N-acylethanolamine-hydrolyzing acid amidase
Ligand
BDBM319810
Substrate
n/a
Meas. Tech.
Determining Endocannabinoid Hydrolase Activity
IC50
>100000±n/a nM
Citation
 Liu, Z; Qiu, Y; Ren, J; Li, Y; Yang, L; Zhu, C Substituted heterocyclic derivative, preparation method and use thereof US Patent  US10174015 Publication Date 1/8/2019 
Target
Name:
N-acylethanolamine-hydrolyzing acid amidase
Synonyms:
ASAH-like protein | ASAHL | Acid ceramidase-like protein | N-acylethanolamine-hydrolyzing acid amidase | N-acylsphingosine amidohydrolase-like | N-acylsphingosine-amidohydrolase | NAAA | NAAA_HUMAN | PLT
Type:
Enzyme
Mol. Mass.:
40073.12
Organism:
Homo sapiens (Human)
Description:
Q02083
Residue:
359
Sequence:
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
  
Inhibitor
Name:
BDBM319810
Synonyms:
US10174015, Compound 23
Type:
Small organic molecule
Emp. Form.:
C21H24N2O4
Mol. Mass.:
368.4263
SMILES:
CN(C)C[C@@H]1COC(=O)N1C(=O)c1ccc(OCCc2ccccc2)cc1 |r|
Structure:
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