Reaction Details Report a problem with these data
Target
Major surface glycoprotein G
Ligand
BDBM194739
Substrate
n/a
Meas. Tech.
Viral Cytopathic Effect (CPE) Assay
Citation
 Gao, L; Guo, L; Liang, C; Wang, B; Wang, L; Yun, H; Zhang, W; Zheng, X Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection US Patent  US9670211 Publication Date 6/6/2017 
Target
Name:
Major surface glycoprotein G
Synonyms:
Attachment glycoprotein G | G | GLYC_HRSV | Membrane-bound glycoprotein | mG
Type:
Protein
Mol. Mass.:
32805.15
Organism:
Human respiratory syncytial virus A (strain Long)
Description:
P20895
Residue:
298
Sequence:
MSKNKDQRTAKTLEKTWDTLNHLLFISSGLYKLNLKSIAQITLSILAMIISTSLIITAIIFIASANHKVTLTTAIIQDATSQIKNTTPTYLTQDPQLGISFSNLSEITSQTTTILASTTPGVKSNLQPTTVKTKNTTTTQTQPSKPTTKQRQNKPPNKPNNDFHFEVFNFVPCSICSNNPTCWAICKRIPNKKPGKKTTTKPTKKPTFKTTKKDLKPQTTKPKEVPTTKPTEEPTINTTKTNITTTLLTNNTTGNPKLTSQMETFHSTSSEGNLSPSQVSTTSEHPSQPSSPPNTTRQ
  
Inhibitor
Name:
BDBM194739
Synonyms:
US9670211, 2-7
Type:
Small organic molecule
Emp. Form.:
C23H23ClN4O2
Mol. Mass.:
422.907
SMILES:
OC1CCC(CC1)n1c(CN2C(=O)C3(CC3)c3ccncc23)nc2cc(Cl)ccc12 |(.94,6.53,;.54,5.04,;1.63,3.95,;1.23,2.46,;-.25,2.07,;-1.34,3.16,;-.94,4.64,;-.65,.58,;.25,-.67,;1.79,-.67,;2.56,-2,;4.1,-2,;4.87,-.67,;4.58,-3.47,;5.35,-4.8,;6.12,-3.47,;3.33,-4.37,;3.17,-5.9,;1.76,-6.53,;.52,-5.62,;.68,-4.09,;2.09,-3.47,;-.65,-1.91,;-2.12,-1.44,;-3.45,-2.21,;-4.78,-1.44,;-6.12,-2.21,;-4.78,.1,;-3.45,.87,;-2.12,.1,)|
Structure:
Search PDB for entries with ligand similarity: