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Target
Glutamate metabotropic receptor 5
Ligand
BDBM82355
Substrate
n/a
Ki
2870±n/a nM
Comments
PDSP_3205
Citation
 Joly, C; Gomeza, J; Brabet, I; Curry, K; Bockaert, J; Pin, JP Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J Neurosci 15:3970-81 (1995) [PubMed] 
Target
Name:
Glutamate metabotropic receptor 5
Synonyms:
metabotropic glutamate 5a | metabotropic glutamate 5b
Type:
Enzyme Catalytic Domain
Mol. Mass.:
120646.45
Organism:
PORCINE
Description:
metabotropic glutamate 5a 0 PORCINE::H0VDS0
Residue:
1094
Sequence:
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISAEEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMRKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSVHINKKENLNQTAVIKPFPKSTESRGLGAGAGRRGGATGPTGGAGAASCAGAGPGGPEPPDAGAKALYDVAEGEEPFAAASVRPRSPSPISTLSQRAGSGGRTDDDVPSLHSEPAARSSSSQGSLMEQISSVVTSLSRANISELQLMMLSTGAPGPRGGRP
  
Inhibitor
Name:
BDBM82355
Synonyms:
Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Ibotenic acid) | CAS_2552-55-8 | CHEMBL284895 | Ibotenate | Ibotenic acid | NSC_1233
Type:
Small organic molecule
Emp. Form.:
C5H6N2O4
Mol. Mass.:
158.1121
SMILES:
NC(C(O)=O)c1cc(=O)[nH]o1
Structure:
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