Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 1
Ligand
BDBM50496697
Substrate
n/a
Meas. Tech.
ChEMBL_1329163 (CHEMBL3225179)
Ki
143±n/a nM
Citation
 East, JE; Carter, KM; Kennedy, PC; Schulte, NA; Toews, ML; Lynch, KR; Macdonald, TL Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist. Medchemcomm 2:325-330 (2011) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
  
Inhibitor
Name:
BDBM50496697
Synonyms:
CHEMBL3218460
Type:
Small organic molecule
Emp. Form.:
C34H50F3N2O6P
Mol. Mass.:
670.7396
SMILES:
CCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1)\C=C\P(O)(O)=O |r|
Structure:
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