Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50105731
Substrate
n/a
Meas. Tech.
ChEMBL_304378 (CHEMBL829020)
EC50
1.1±n/a nM
Citation
 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hübner, H; Gmeiner, P CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists. J Med Chem 48:2493-508 (2005) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50105731
Synonyms:
(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde | CHEMBL316983
Type:
Small organic molecule
Emp. Form.:
C15H24N2O
Mol. Mass.:
248.3639
SMILES:
CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O
Structure:
Search PDB for entries with ligand similarity: