Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50306407
Substrate
n/a
Meas. Tech.
ChEMBL_609846 (CHEMBL1072787)
EC50
203±n/a nM
Citation
 Zhou, C; Tang, C; Chang, E; Ge, M; Lin, S; Cline, E; Tan, CP; Feng, Y; Zhou, YP; Eiermann, GJ; Petrov, A; Salituro, G; Meinke, P; Mosley, R; Akiyama, TE; Einstein, M; Kumar, S; Berger, J; Howard, AD; Thornberry, N; Mills, SG; Yang, L Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists. Bioorg Med Chem Lett 20:1298-301 (2010) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50306407
Synonyms:
5-(4-(m-tolyloxy)benzyl)thiazolidine-2,4-dione | CHEMBL597638
Type:
Small organic molecule
Emp. Form.:
C17H15NO3S
Mol. Mass.:
313.371
SMILES:
Cc1cccc(Oc2ccc(Cc3sc(=O)[nH]c3O)cc2)c1
Structure:
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