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Target
D-alanyl-D-alanine carboxypeptidase
Ligand
BDBM50385267
Substrate
n/a
Meas. Tech.
ChEMBL_822544 (CHEMBL2039477)
Ki
1500±n/a nM
Citation
 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C. Bioorg Med Chem 20:3915-24 (2012) [PubMed]  Article 
Target
Name:
D-alanyl-D-alanine carboxypeptidase
Synonyms:
DAC_ACTSP | dac
Type:
PROTEIN
Mol. Mass.:
54928.46
Organism:
Actinomadura sp. (strain R39)
Description:
ChEMBL_822544
Residue:
538
Sequence:
MKQSSPEPLRPRRTGGRGGARRAAALVTIPLLPMTLLGASPALADASGARLTELREDIDAILEDPALEGAVSGVVVVDTATGEELYSRDGGEQLLPASNMKLFTAAAALEVLGADHSFGTEVAAESAPGRRGEVQDLYLVGRGDPTLSAEDLDAMAAEVAASGVRTVRGDLYADDTWFDSERLVDDWWPEDEPYAYSAQISALTVAHGERFDTGVTEVSVTPAAEGEPADVDLGAAEGYAELDNRAVTGAAGSANTLVIDRPVGTNTIAVTGSLPADAAPVTALRTVDEPAALAGHLFEEALESNGVTVKGDVGLGGVPADWQDAEVLADHTSAELSEILVPFMKFSNNGHAEMLVKSIGQETAGAGTWDAGLVGVEEALSGLGVDTAGLVLNDGSGLSRGNLVTADTVVDLLGQAGSAPWAQTWSASLPVAGESDPFVGGTLANRMRGTAAEGVVEAKTGTMSGVSALSGYVPGPEGELAFSIVNNGHSGPAPLAVQDAIAVRLAEYAGHQAPEGARMMRGPVQGSGELECSWVQAC
  
Inhibitor
Name:
BDBM50385267
Synonyms:
CHEMBL2035284
Type:
Small organic molecule
Emp. Form.:
C10H14BNO5
Mol. Mass.:
239.033
SMILES:
COc1cccc(OC)c1C(=O)NCB(O)O
Structure:
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