Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate assessed as inhibition...More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0480nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0780nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 84nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 93nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 298nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Binding affinity to Actinomadura sp. R39 PBPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 750nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Binding affinity to Actinomadura sp. R39 PBPMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+4nMAssay Description:Binding affinity to Actinomadura sp. R39 PBPMore data for this Ligand-Target Pair
Affinity DataKi: 1.25E+5nMAssay Description:Binding affinity to Actinomadura sp. R39 PBPMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of G9a (unknown origin) using biotinylated histone monomethyl-H3K9 peptide by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataIC50: 382nMAssay Description:Inhibition of DNMT1 (unknown origin) using biotinylated histone monomethyl-H3K9 peptide by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x after 60 mins by SDS-PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MM6 cell adhesion to recombinant E-selectin by flow chamber assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MM6 cell adhesion to recombinant E-selectin by flow chamber assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of MM6 cell adhesion to recombinant E-selectin by flow chamber assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of Actinomadura R39 PBP after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propi...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propi...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometryMore data for this Ligand-Target Pair