Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50394222
Substrate
n/a
Meas. Tech.
ChEMBL_856722 (CHEMBL2162548)
IC50
1.01±n/a nM
Citation
 Tamura, Y; Omori, N; Kouyama, N; Nishiura, Y; Hayashi, K; Watanabe, K; Tanaka, Y; Chiba, T; Yukioka, H; Sato, H; Okuno, T Identification of a novel and orally available benzimidazole derivative as an NPY Y5 receptor antagonist with in vivo efficacy. Bioorg Med Chem Lett 22:6554-8 (2012) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r
Type:
Enzyme
Mol. Mass.:
52807.91
Organism:
Mus musculus (Mouse)
Description:
O70342
Residue:
466
Sequence:
MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
  
Inhibitor
Name:
BDBM50394222
Synonyms:
CHEMBL2159174
Type:
Small organic molecule
Emp. Form.:
C20H23N3O2S
Mol. Mass.:
369.481
SMILES:
CCCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCC(C1)c1ccccc1
Structure:
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