Target
Free fatty acid receptor 4
Ligand
BDBM50207053
Substrate
n/a
Meas. Tech.
ChEMBL_1629516 (CHEMBL3872142)
EC50
130±n/a nM
Citation
 Adams, GLVelazquez, FJayne, CShah, UMiao, SAshley, ERMadeira, MAkiyama, TEDi Salvo, JSuzuki, TWang, NTruong, QGilbert, EZhou, DVerras, AKirkland, MPachanski, MPowles, MYin, WUjjainwalla, FVenkatraman, SEdmondson, SD Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with ACS Med Chem Lett 8:96-101 (2017) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50207053
Synonyms:
CHEMBL3950444
Type:
Small organic molecule
Emp. Form.:
C20H16F4O4
Mol. Mass.:
396.3323
SMILES:
[H][C@@]1(C[C@]1([H])[C@@]1([H])CCc2cc(ccc2O1)-c1cc(OC(F)(F)F)ccc1F)C(O)=O |r|
Structure:
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