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Target
Sporulation kinase A
Ligand
BDBM50215984
Substrate
n/a
Meas. Tech.
ChEMBL_92720 (CHEMBL872510)
IC50
>500000±n/a nM
Citation
 Sui, Z; Guan, J; Hlasta, DJ; Macielag, MJ; Foleno, BD; Goldschmidt, RM; Loeloff, MJ; Webb, GC; Barrett, JF SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities. Bioorg Med Chem Lett 8:1929-34 (1998) [PubMed]  Article 
Target
Name:
Sporulation kinase A
Synonyms:
KINA_BACSU | Sporulation kinase A | Stage II sporulation protein F | Stage II sporulation protein J | gsiC | kinA | scoD | spoIIF | spoIIJ
Type:
PROTEIN
Mol. Mass.:
69161.05
Organism:
Bacillus subtilis (strain 168)
Description:
ChEMBL_105028
Residue:
606
Sequence:
MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQFLVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGHQSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSKDAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYKNQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFEAATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCIPTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFPKK
  
Inhibitor
Name:
BDBM50215984
Synonyms:
CHEMBL291781
Type:
Small organic molecule
Emp. Form.:
C15H11Cl2N3O2
Mol. Mass.:
336.173
SMILES:
COc1ccc(cc1)-c1n[nH]c(n1)-c1cc(Cl)cc(Cl)c1O
Structure:
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