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Target
Oxytocin receptor
Ligand
BDBM50219720
Substrate
n/a
Meas. Tech.
ChEMBL_149055 (CHEMBL761409)
Ki
10.0±n/a nM
Citation
 Wyatt, PG; Allen, MJ; Chilcott, J; Foster, A; Livermore, DG; Mordaunt, JE; Scicinski, J; Woollard, PM Identification of potent and selective oxytocin antagonists. Part 1: indole and benzofuran derivatives. Bioorg Med Chem Lett 12:1399-404 (2002) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM50219720
Synonyms:
CHEMBL32745
Type:
Small organic molecule
Emp. Form.:
C29H34N4O5S
Mol. Mass.:
550.669
SMILES:
Cc1cc(cc2ccn(C[C@H]3CCCN3S(C)(=O)=O)c12)C(=O)N1CCC(CC1)N1C(=O)OCc2ccccc12
Structure:
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