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Target
G-protein coupled receptor 39
Ligand
BDBM50232382
Substrate
n/a
Meas. Tech.
ChEMBL_1646463 (CHEMBL3995519)
EC50
5.0±n/a nM
Citation
 Frimurer, TM; Mende, F; Graae, AS; Engelstoft, MS; Egerod, KL; Nygaard, R; Gerlach, LO; Hansen, JB; Schwartz, TW; Holst, B Model-Based Discovery of Synthetic Agonists for the Zn J Med Chem 60:886-898 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 39
Synonyms:
GPR39 | GPR39_HUMAN
Type:
PROTEIN
Mol. Mass.:
51351.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107977
Residue:
453
Sequence:
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
  
Inhibitor
Name:
BDBM50232382
Synonyms:
CHEMBL4090669
Type:
Small organic molecule
Emp. Form.:
C22H22N8O2
Mol. Mass.:
430.4625
SMILES:
CCC(C(=O)NC1CC(=O)Nc2c1c(C)nn2-c1ncnc2nc[nH]c12)c1ccccc1
Structure:
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