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Target
Nuclear hormone receptor family member daf-12
Ligand
BDBM50171428
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12)
EC50
67527±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear hormone receptor family member daf-12
Synonyms:
DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
84211.49
Organism:
Caenorhabditis elegans
Description:
gi_71987181
Residue:
753
Sequence:
MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQMSTPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRVCGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFTVGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYPPQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLTMMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLMNEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIPGNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAMIPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQMQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGVTRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAVYLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALGLLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
  
Inhibitor
Name:
BDBM50171428
Synonyms:
5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEMBL191015 | cid_784811
Type:
Small organic molecule
Emp. Form.:
C13H10N2OS
Mol. Mass.:
242.296
SMILES:
Cc1ccc(cc1)-c1noc(n1)-c1cccs1
Structure:
Search PDB for entries with ligand similarity: