BDBM50171428 5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole::CHEMBL191015::cid_784811

SMILES Cc1ccc(cc1)-c1noc(n1)-c1cccs1

InChI Key InChIKey=ZBIZYSIIJRBDSE-UHFFFAOYSA-N

Data  2 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171428   

TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataEC50:  2.29E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein skinhead-1(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataIC50:  1.24E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock protein hsp-16.2(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataIC50: >6.40E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50171428(5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole | CHEM...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay