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Target
Acetylcholinesterase
Ligand
BDBM152510
Substrate
n/a
Meas. Tech.
Acetylcholinesterase Inhibition Assay
pH
8±n/a
Ki
3.24±0.0 nM
IC50
4.88±0.0 nM
Comments
extracted
Citation
 Öztaskin, N; Çetinkaya, Y; Taslimi, P; Göksu, S; Gülçin, Ä° Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives. Bioorg Chem 60:49-57 (2015) [PubMed]  Article 
Target
Name:
Acetylcholinesterase
Synonyms:
ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE)
Type:
Enzyme
Mol. Mass.:
67792.70
Organism:
Homo sapiens (Human)
Description:
P22303
Residue:
614
Sequence:
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
  
Inhibitor
Name:
BDBM152510
Synonyms:
(4-Bromo-2,5-dihydroxyphenyl)(phenyl)methanone (23)
Type:
Small organic molecule
Emp. Form.:
C13H9BrO3
Mol. Mass.:
293.113
SMILES:
Oc1cc(C(=O)c2ccccc2)c(O)cc1Br
Structure:
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