Compile Data Set for Download or QSAR
maximum 50k data
Found 459 with Last Name = 'taslimi' and Initial = 'p'
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152509((4-Bromo-2,5-dihydroxyphenyl)(4-hydroxyphenyl)meth...)
Affinity DataKi:  2.78nM IC50:  4.58nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152510((4-Bromo-2,5-dihydroxyphenyl)(phenyl)methanone (23...)
Affinity DataKi:  3.24nM IC50:  4.88nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152500((2-bromo-4-methoxyphenyl)(3,4-dimethoxyphenyl)meth...)
Affinity DataKi:  3.53nM IC50:  4.41nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152506((5-bromo-2,4-dimethoxyphenyl)(4-methoxyphenyl)meth...)
Affinity DataKi:  3.65nM IC50:  4.05nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152508((2-Bromo-4-hydroxyphenyl)(2,3-dihydroxyphenyl)meth...)
Affinity DataKi:  3.75nM IC50:  4.84nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152503((4-Bromo-2,5-dimethoxyphenyl)(4-methoxyphenyl)meth...)
Affinity DataKi:  3.77nM IC50:  4.22nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50275934((2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)thia...)
Affinity DataKi:  4nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152507((2-bromo-4-hydroxyphenyl)(3,4-dihydroxyphenyl)meth...)
Affinity DataKi:  4.06nM IC50:  4.71nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152502(2-bromo-1,4-dimethoxybenzene (14))
Affinity DataKi:  4.25nM IC50:  7.21nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152501((2-Bromo-4-methoxyphenyl)(2,3-dimethoxyphenyl)meth...)
Affinity DataKi:  4.34nM IC50:  4.20nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152504((4-Bromo-2,5-dimethoxyphenyl)(phenyl)methanone (16...)
Affinity DataKi:  5.28nM IC50:  4.68nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152511((5-Bromo-2,4-dihydroxyphenyl)(4-hydroxyphenyl)meth...)
Affinity DataKi:  5.72nM IC50:  4.81nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM152505((2,4-dimethoxyphenyl)(4-methoxyphenyl)methanone (1...)
Affinity DataKi:  5.88nM IC50:  5.25nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM14028((S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]...)
Affinity DataKi:  6nM ΔG°:  -47.7kJ/molepH: 7.6 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097177(CHEMBL3581126)
Affinity DataKi:  7nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  7.64nM IC50:  7.53nMpH: 8.0Assay Description:AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276015(CHEMBL509161 | N-(3,5-dimethylphenyl)-4-(thiazol-2...)
Affinity DataKi:  8nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50275935((S)-2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-...)
Affinity DataKi:  9nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097155(CHEMBL3581132)
Affinity DataKi:  10nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276065((2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)thia...)
Affinity DataKi:  10nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50275358((2-(2-(3-methyl-5-(trifluoromethyl)phenylamino)pyr...)
Affinity DataKi:  10nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097166(CHEMBL3580669)
Affinity DataKi:  10nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276018(1-(3-(cyclopenta-1,3-dienyl)benzyl)-3,5-diethylben...)
Affinity DataKi:  14nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097174(CHEMBL3581129)
Affinity DataKi:  17nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097165(CHEMBL3581146)
Affinity DataKi:  18nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097152(CHEMBL3581149)
Affinity DataKi:  22nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249284(2-(4-methyl-2-(2-(3-methyl-5-(trifluoromethyl)phen...)
Affinity DataKi:  22nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276064(CHEMBL470780 | N-(3,5-dimethylphenyl)-4-(5-methylt...)
Affinity DataKi:  23nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50275357(CHEMBL451450 | N-(3-methoxy-5-(trifluoromethyl)phe...)
Affinity DataKi:  23nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249286(3-(3-(4-(thiazol-2-yl)pyrimidin-2-ylamino)-5-(trif...)
Affinity DataKi:  26nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097175(CHEMBL3581128)
Affinity DataKi:  26nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276016(CHEMBL512319 | N-(3-methoxy-5-(trifluoromethyl)phe...)
Affinity DataKi:  28nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097351(CHEMBL3581123)
Affinity DataKi:  28nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097153(CHEMBL3581150)
Affinity DataKi:  30nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297454(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  30nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249318(2-(2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-4...)
Affinity DataKi:  32nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase WNK1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50258546(CHEMBL4087727)
Affinity DataKi:  32nMAssay Description:Allosteric inhibition of WNK1 (unknown origin) expressed in HEK293 cells co-expressing flag-OSR1 assessed as reduction in sorbitol-stimulated OSR1 ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50275355((2-(2-(3-methoxy-5-(trifluoromethyl)phenylamino)py...)
Affinity DataKi:  33nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276017(3-(4-(thiazol-2-yl)pyrimidin-2-ylamino)-5-(trifluo...)
Affinity DataKi:  44nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097167(CHEMBL3581147)
Affinity DataKi:  44nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097151(CHEMBL3581148)
Affinity DataKi:  45nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50275356(3-(4-(4-(hydroxymethyl)thiazol-2-yl)pyrimidin-2-yl...)
Affinity DataKi:  50nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249356(CHEMBL453217 | N-(3,5-dimethylphenyl)-4-(4-methylt...)
Affinity DataKi:  56nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099331(4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataKi:  60nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097171(CHEMBL3581133)
Affinity DataKi:  61nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297455(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  70nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097340(CHEMBL3581124)
Affinity DataKi:  70nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097355(CHEMBL3581119)
Affinity DataKi:  81nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50276063(4-(thiazol-2-yl)-N-m-tolylpyrimidin-2-amine | CHEM...)
Affinity DataKi:  82nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM50097169(CHEMBL3581135)
Affinity DataKi:  89nMAssay Description:Inhibition of ROCK1 (6 to 553 amino acids) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 459 total ) | Next | Last >>
Jump to: