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Compounds Sorted by Binding Targets per Compound

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429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • β-Carbonic anhydrase 2 (CA 2)
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • Delta carbonic anhydrase
  • beta-Carbonic Anhydrase
89 Ki 5 IC50 6 Kd
  • 4-methylbenzene-1-sulfonamide
  • CHEMBL574
  • aromatic/heteroaromatic sulfonamide 4
  • hCA inhibitor, 7
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Gag-Pol polyprotein
  • Gag-Pol polyprotein (Capsid Protein)
  • HIV-1 Reverse Transcriptase
  • HIV-1 Reverse Transcriptase Mutant (K103N)
  • HIV-1 Reverse Transcriptase Mutant (L100I)
  • HIV-1 Reverse Transcriptase Mutant (L100I/K103N)
  • HIV-1 Reverse Transcriptase Mutant (P236L)
  • HIV-1 Reverse Transcriptase Mutant (V106A)
  • HIV-1 Reverse Transcriptase Mutant (V179D)
  • HIV-1 Reverse Transcriptase Mutant (Y181C)
  • HIV-1 Reverse Transcriptase Mutant (Y181I)
  • HIV-1 Reverse Transcriptase Mutant (Y188L)
  • HIV-1 Reverse transcriptase (HIV-1 RT)
  • HIV-2 Reverse Transcriptase
  • Human immunodeficiency virus type 1 reverse transcriptase
  • Multidrug resistance-associated protein 4
  • Reverse Transcriptase
  • Reverse Transcriptase (HIV-1 K103N RT)
  • Reverse transcriptase
  • Reverse transcriptase (HIV-1 RT)(1-350)
32 Ki 225 IC50 27 EC50
1 ΔG°
  • 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2 ,3 -e][1,4]diazepin-6-one
  • 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
  • BI-RG-587
  • CHEMBL57
  • Nevirapine
  • Nevirapine (NVP)
  • Viramune
  • Cystine/glutamate transporter
  • GRIA3
  • GRIK4
  • GRM7
  • Glutamate Carboxypeptidase II (GCPII)
  • Glutamate kainate
  • Glutamate receptor ionotropic, NMDA 1
  • Glutamate receptor ionotropic, kainate
  • Glutamate receptor ionotropic, kainate 1
  • Ionotropic glutamate receptor kainate 2/5
  • Metabotropic Glutamate 1a
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 3
  • Metabotropic glutamate receptor 4 (mGlu4)
  • Metabotropic glutamate receptor 4 (mGluR4)
  • Metabotropic glutamate receptor 5
  • Metabotropic glutamate receptor 6
  • Metabotropic glutamate receptor 6 (mGlu6)
  • Metabotropic glutamate receptor 7 (mGlu7)
  • Metabotropic glutamate receptor 8
  • metabotropic glutamate 5a
38 Ki 2 IC50 21 EC50
  • (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
  • 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid
  • CHEMBL279956
  • Quisqualate
  • Quisqualate, L
  • quisqualic acid
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Lysine-specific demethylase 2B
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 3B (KDM3B)
  • Lysine-specific demethylase 4A
  • Lysine-specific demethylase 4A (KDM4A)
  • Lysine-specific demethylase 4B
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5A (KDM5A(aa 1-1090)-Flag)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-588)ΔAP)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-739)ΔAP(2C-2S))
  • Lysine-specific demethylase 5A (KDM5A)
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5B (KDM5B(aa 1-604)ΔAP)
  • Lysine-specific demethylase 5B (KDM5B(aa 1-755)ΔAP)
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 5C (KDM5C(aa 1-789)ΔAP)
  • Lysine-specific demethylase 5C (KDM5C)
  • Lysine-specific demethylase 5D (KDM5D(aa 1-760)ΔAP)
  • Lysine-specific demethylase 5D (KDM5D)
  • Lysine-specific demethylase 6A
  • Lysine-specific demethylase 6B
40 IC50 2 Kd
  • 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid (KDM5-C49)
  • KDM5-C49
  • KDOAM-20
  • Alpha-glucosidase MAL12
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • D(1A) dopamine receptor
  • Epidermal growth factor receptor
  • Gamma-amino-N-butyrate transaminase
  • Procollagen-proline,2-oxoglutarate-4-dioxygenase
  • Succinate semialdehyde dehydrogenase
  • Thiopurine S-methyltransferase
  • Toll-like receptor 2
  • Tyrosinase
31 Ki 8 IC50 1 EC50
  • 4-Hydroxybenzoate, III
  • 4-hydroxybenzoic acid
  • CHEMBL441343
  • p-Hydroxybenzoic acid
  • phenol derivative, 8
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Gamma-carbonic anhydrase
  • beta-Carbonic Anhydrase
98 Ki
  • CHEMBL355001
  • H2NSO2NH2
  • sulfamamide
  • sulfamide
  • sulfamoylamine
  • 3C-like protease
  • 5-hydroxytryptamine receptor 1A
  • BZLF2
  • Cathepsin B
  • Dual Specificity Protein Phosphatase 1
  • Dual specificity phosphatase Cdc25B
  • Heat shock protein HSP 90-alpha
  • Heat shock protein HSP 90-beta
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Lipoamide Dehydrogenase (Lpd)
  • MKP-3
  • Mitogen-activated protein kinase 10
  • Nuclear receptor ROR-alpha
  • Procathepsin L
  • Pyruvate dehydrogenase (PDH)
  • Serotonin (5-HT) receptor
  • Sphingosine 1-phosphate receptor 1
  • Sphingosine 1-phosphate receptor 3
  • Steroidogenic Factor 1
  • diphosphomevalonate decarboxylase
  • heat shock protein 90
  • streptokinase A precursor
44 IC50 2 Kd 6 EC50
  • 1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
  • 1-ethyl-6-methyl-3-phenyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
  • 1-ethyl-6-methyl-3-phenyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone
  • 1-ethyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
  • MLS000027832
  • SMR000008919
  • US9073941, 602
  • cid_647501
  • Apoptosis regulator Bcl-2
  • Apoptotic peptidase activating factor 1
  • Axin-1/Glycogen synthase kinase-3 beta
  • BCL-W
  • Bcl-2-related protein A1
  • Caspase-9
  • DNA damage-inducible transcript 3 protein
  • DNA repair protein RAD51 homolog 1
  • G protein signalling regulator 19
  • G-protein coupled receptor 35
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Isoform Bcl-X(L)
  • LAP4
  • Microtubule-associated protein Tau isoform 2N4R (Tau 2N4R)
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • Phospholipase A2
  • RGS7
  • RPL19A
  • Regulator of G-protein signaling 8
  • XBP1
  • cysteine protease ATG4B isoform a
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
12 IC50 15 EC50
  • (2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methyl-prop-2-enylidene]-1,3-benzothiazole;iodide
  • (2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methylprop-2-enylidene]-1,3-benzothiazole;iodide
  • Cyanines, 1
  • MLS001018610
  • SMR000354813
  • cid_6364517
  • Apoptosis regulator Bcl-2
  • Apoptotic peptidase activating factor 1
  • BCL-W
  • Bcl-2-related protein A1
  • Beta-galactosidase
  • C-C chemokine receptor type 6 (CCR6)
  • Caspase-9
  • Estradiol receptor beta (ERβ)
  • G protein signalling regulator 19
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • Homo sapiens huntingtin (HTT), mRNA
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • NCOA2 protein
  • RGS7
  • Regulator of G-protein signaling 8
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
  • glutathione S-transferase
  • nuclear receptor coactivator 1 isoform 1
  • nuclear receptor coactivator 3 isoform a
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
  • streptokinase A precursor
13 IC50 14 EC50
  • 2,5-bis(chloranyl)-3-[2-(dimethylamino)-1,3-thiazol-5-yl]-6-pyrrolidin-1-yl-cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-[2-(dimethylamino)-1,3-thiazol-5-yl]-6-(1-pyrrolidinyl)benzo-1,4-quinone
  • 2,5-dichloro-3-[2-(dimethylamino)-1,3-thiazol-5-yl]-6-pyrrolidin-1-ylcyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-[2-(dimethylamino)-5-thiazolyl]-6-(1-pyrrolidinyl)cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-[2-(dimethylamino)thiazol-5-yl]-6-pyrrolidino-p-benzoquinone
  • MLS000548208
  • SMR000115102
  • cid_1002248
  • ATP synthase subunit gamma, mitochondrial
  • ATP-binding cassette sub-family G member 2
  • Alpha-chymotrypsin
  • Beta-lactamase AmpC
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • CDGSH iron-sulfur domain-containing protein 1
  • Canalicular multispecific organic anion transporter 2
  • Cholesteryl ester transfer protein
  • Cystic fibrosis transmembrane conductance regulator
  • Malate dehydrogenase cytoplasmic
  • Multidrug resistance-associated protein 4
  • NACHT, LRR and PYD domains-containing protein 3
  • NLRP3 protein
  • Oligopeptide transporter, kidney isoform
  • Peroxisome proliferator-activated receptor
  • Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1
  • Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2
  • Potassium voltage-gated channel subfamily H member 2
  • Solute carrier family 15 member 1
  • Solute carrier family 22 member 6
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
8 Ki 31 IC50 1 EC50
  • 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
  • 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
  • 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide
  • 5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
  • CHEMBL472
  • GLYBURIDE
  • Glibenclamide
  • ATP-binding cassette sub-family G member 2
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor A1
  • Ah Receptor
  • Carboxylic ester hydrolase
  • Cytochrome P450 19A1
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Cytochrome P450 3A6
  • DNA-dependent protein kinase
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A4
  • Uridine-5'-diphosphoglucuronosyltransferase 1A6
  • Uridine-5'-diphosphoglucuronosyltransferase 2B10
  • Uridine-5'-diphosphoglucuronosyltransferase 2B7
9 Ki 114 IC50 4 EC50
  • 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE
  • 2-Phenyl-benzo[h]chromen-4-one
  • 7,8-Benzoflavone
  • CHEMBL283196
  • alpha-naphthoflavone
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • DRD2
  • Dopamine D2 receptor
  • Dopamine receptor
  • HTR1D
  • HTR6
  • Histamine H1 receptor
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M2
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • adrenergic Alpha2
61 Ki 13 IC50
  • (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide
  • (S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide
  • 3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide
  • 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide
  • 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide
  • 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)
  • 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)
  • CHEMBL22242
  • REMOXIPRIDE
  • Aldose reductase
  • Aldose reductase (AR)
  • Arachidonate 5-lipoxygenase
  • Baculoviral IAP repeat-containing protein 2/Estrogen receptor
  • Bcl-2-like protein 11
  • Beta amyloid A4 protein
  • Beta-secretase 1
  • Cyclooxygenase
  • Cytochrome P450 19A1
  • Estradiol 17-beta-dehydrogenase 1
  • Estradiol 17-beta-dehydrogenase 2
  • Estrogen receptor
  • Human immunodeficiency virus type 1 integrase
  • Monoamine oxidase
  • NLRP3 protein
  • Neuraminidase
  • Neuronal acetylcholine receptor protein alpha-7 subunit
  • Probable global transcription activator SNF2L2
  • Proteasome subunit beta type-1/beta type-5
  • Protein-tyrosine phosphatase 1B
  • Sialidase
  • Tyrosyl-DNA phosphodiesterase 1
  • Xanthine dehydrogenase
32 IC50 3 EC50
  • (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone
  • (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
  • 1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone
  • 1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one
  • 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
  • 2',4',4-trihydroxychalcone
  • 2',4,4'-trihydroxychalcone
  • 2,4'-dihydroxy-4-hydroxychalcone
  • CHEMBL129795
  • Isoliquiritigenin (1)
  • cid_638278
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase (2 and 3)
  • Matrix metalloproteinase 10
  • Matrix metalloproteinase 15
  • Matrix metalloproteinase 16
  • Matrix metalloproteinase 26
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-20
  • Matrix metalloproteinase-24
  • Matrix metalloproteinase-25
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
  • TNF-alpha
  • Zinc metalloproteinase dpy-31
15 Ki 81 IC50
  • (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide
  • CHEMBL279785
  • cid_119031
  • marimastat
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
26 Ki
  • 3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL28607
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
23 Ki
  • 3-[4-(4-Ethyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL282829
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
23 Ki
  • 3-[4-(4-Vinyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL29808
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
23 Ki
  • 3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL283036
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
23 Ki
  • 3-[4-(4-Propyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL28833
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
23 Ki
  • 3-(4-Biphenyl-4-yl-piperazin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL287671
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adenosine receptor A3
  • Adrenergic receptor alpha-1
  • Cannabinoid receptor 1
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Vasopressin V1a receptor
  • Voltage-gated L-type calcium channel
23 IC50
  • CHEMBL116463
  • {1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-carbamic acid 2-(4-cyano-phenyl)-ethyl ester
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 2
  • Cereblon/Histone deacetylase 4
  • Cereblon/Histone deacetylase 6
  • Histone deacetylase
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphoinositide 3-Kinase (PI3K), delta
  • mTOR/FKBP12A/FKBP12B
  • p110α/p85α
  • p110β/p85α
47 IC50 1 EC50
  • CHEMBL3622533
  • Atypical chemokine receptor 2
  • C-C chemokine receptor type 2
  • C-C chemokine receptor type 3
  • C-C chemokine receptor type 4
  • C-C chemokine receptor type 6
  • C-C chemokine receptor type 6 (CCR6)
  • C-C chemokine receptor type 7
  • C-C chemokine receptor type 8
  • C-C chemokine receptor type 9
  • C-X-C chemokine receptor type 1
  • C-X-C chemokine receptor type 2
  • C-X-C chemokine receptor type 3
  • C-X-C chemokine receptor type 4
  • C-X-C chemokine receptor type 5
  • C-X-C chemokine receptor type 5 isoform 1
  • C-X-C chemokine receptor type 6
  • C-X-C chemokine receptor type 7
  • C-X-C chemokine receptor type 7 (CXCR7)
  • C-X3-C chemokine receptor 1
  • CCR5/mu opioid receptor complex
  • Chemokine-like receptor 1
  • G-protein coupled receptor ChemR23
  • chemokine (C-X-C motif) receptor 3
21 IC50 18 EC50
  • CHEMBL4067429
  • Angiopoietin-1 receptor
  • Axin-1/Glycogen synthase kinase-3 beta
  • Casein kinase I isoform delta
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent-like kinase 5
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase kinase kinase 1
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Protein kinase C theta type
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase Chk1/2
  • Tyrosine-protein kinase Lck
  • Vascular endothelial growth factor receptor 2
23 IC50
  • (S)-5-(5-methylfuran-2-yl)-3-(4-(methylsulfinyl)phenyl)benzofuran
  • CHEMBL574588
  • Angiopoietin-1 receptor
  • Axin-1/Glycogen synthase kinase-3 beta
  • Casein kinase I isoform delta
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent-like kinase 5
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase kinase kinase 1
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Protein kinase C theta type
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase Chk1/2
  • Tyrosine-protein kinase Lck
  • Vascular endothelial growth factor receptor 2
23 IC50
  • (S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2-yl)benzofuran
  • CHEMBL574613
  • Aurora kinase A/Targeting protein for Xklp2
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 2
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Leukocyte tyrosine kinase receptor
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Protein kinase C alpha type
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
25 IC50
  • (R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylamide
  • CHEMBL602471
  • Aurora kinase A/Targeting protein for Xklp2
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 2
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Leukocyte tyrosine kinase receptor
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Protein kinase C alpha type
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
23 IC50
  • (R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinoline
  • CHEMBL600795
  • Cereblon/Histone deacetylase 6
  • Epidermal growth factor receptor
  • Ferrochelatase R115L (FECH)
  • Fibroblast growth factor receptor 2
  • Histone deacetylase
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Leukotriene A4 hydrolase
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
31 IC50 1 Kd
  • 7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide
  • CHEMBL598797
  • CUDC-101
  • Aurora kinase B
  • Casein kinase I
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit alpha
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • PKC alpha and beta-2
  • Platelet-derived growth factor receptor alpha
  • Protein kinase C alpha type
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 1
  • Ribosomal protein S6 kinase alpha 1
  • Serine/threonine-protein kinase B-raf
  • Serine/threonine-protein kinase Chk1/2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lyn
24 IC50
  • 3-(7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol
  • CHEMBL1087650
  • Cyclin-dependent kinase 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin-like growth factor I receptor
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 11
  • Mitogen-activated protein kinase 12
  • Mitogen-activated protein kinase 13 (MAPK13)
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 8
  • Protein kinase C (PKC)
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • Protein kinase C theta type
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Vascular endothelial growth factor receptor 2
24 IC50
  • CHEMBL1807446
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Epithelial discoidin domain-containing receptor 1
  • Fibroblast growth factor receptor 2
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Leukocyte tyrosine kinase receptor
  • Macrophage-stimulating protein receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
23 IC50
  • CHEMBL1949788
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Epithelial discoidin domain-containing receptor 1
  • Fibroblast growth factor receptor 2
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Leukocyte tyrosine kinase receptor
  • Macrophage-stimulating protein receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
23 IC50
  • CHEMBL1949789
  • ATP-binding cassette sub-family G member 2
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • CDK2/Cyclin A/Cyclin A1
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase B-raf
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
23 IC50
  • CHEMBL1957190
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cyclin-dependent kinase 9
  • Cytochrome P450 3A
  • Fibroblast growth factor receptor 1
  • Glycogen synthase kinase-3
  • Insulin-like growth factor I receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Potassium voltage-gated channel subfamily H member 2
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Rho-associated protein kinase 1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
2 Ki 43 IC50
  • ABT-348
  • ILORASERTIB
  • US8722890, 1
  • US8722890, 2
  • Cyclin-dependent kinase 2
  • Hepatocyte growth factor receptor
  • Lysyl-tRNA synthetase
  • Mitogen-activated protein kinase 10
  • Mitogen-activated protein kinase 3
  • PKC alpha and beta-2
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • Protein kinase C theta type
  • Protein kinase C, epsilon
  • RAF proto-oncogene serine/threonine-protein kinase
  • Rho-associated protein kinase 1
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
16 Ki 8 IC50
  • CHEMBL2046643
  • 1,3-beta-glucan synthase component GLS2
  • ALK tyrosine kinase receptor
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Focal adhesion kinase 1
  • Insulin receptor
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • NUAK family SNF1-like kinase 1
  • Ribosomal protein S6 kinase alpha 1
  • Ribosomal protein S6 kinase alpha 2
  • Ribosomal protein S6 kinase alpha 6
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase CHK2
  • Tyrosine kinase non-receptor protein 2
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase FER
  • Tyrosine-protein kinase Fes/Fps
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 3
29 IC50
  • CHEMBL2064666
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/Cyclin A/Cyclin A1
  • Casein kinase I isoform delta
  • Epidermal growth factor receptor
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Inhibitor of nuclear factor kappa-B kinase subunit epsilon
  • Insulin receptor
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 1
  • P-selectin/P-selectin glycoprotein ligand 1
  • Protein kinase C (PKC)
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase CHK2
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase Sgk1
  • Serine/threonine-protein kinase pim-2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
24 IC50
  • CHEMBL2312301
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • CDK2/Cyclin A/Cyclin A1
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
23 IC50
  • BASTADIN 3
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 9
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Protein kinase C alpha type
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Ribosomal protein S6 kinase (P70S6K)
  • Ribosomal protein S6 kinase alpha 5
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase pim-1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Vascular endothelial growth factor receptor 2
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
24 IC50
  • CHEMBL2347053
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • ALTERTOXIN I
  • Altertoxin I
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • ALTERLACTONE
  • Alterlactone
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • DESMETHYLALTENUSIN
  • Desmethylaltenusin
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • Alternariol 5-O-Sulfate
  • CHEMBL483525
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • ALTERNARIENONIC ACID
  • Alternarienonic Acid
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • CHEMBL520144
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
28 IC50
  • ALTERNARIOL
  • Alternariol
  • CHEBI:64983
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • ALTERPORRIOL G/H
  • Alterporriol G/H
  • CHEBI:65389
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • 6-O-Methylalaternin
  • CHEMBL556684
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • MACROSPORIN
  • Macrosporin
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
24 IC50
  • ALTERSOLANOL A
  • Altersolanol A
  • CHEBI:2615
  • ATP-binding cassette sub-family G member 2
  • Adrenergic Alpha
  • Apurinic-apyrimidinic endonuclease 1 (APE-1)
  • Cystic fibrosis transmembrane conductance regulator
  • Cytochrome P450 2D6 (2D6)
  • DNA-3-methyladenine glycosylase
  • Group III secretory phopholipase A2
  • Human immunodeficiency virus type 1 integrase
  • LANA
  • Multidrug and toxin extrusion protein 1
  • Multidrug and toxin extrusion protein 2
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • NEDD8-activating enzyme E1 catalytic subunit
  • Purinergic receptor P2Y12
  • Serine/threonine-protein kinase 33
  • Serine/threonine-protein kinase pim-1
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • TAR DNA-binding protein 43
  • Topoisomerase II alpha (HuTopoIIα)
  • Tyrosine-protein kinase BTK
  • Voltage-gated L-type calcium channel
2 Ki 27 IC50 4 EC50
  • 1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis(oxidanyl)anthracene-9,10-dione;hydrochloride
  • 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-9,10-anthraquinone;hydrochloride
  • 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;hydrochloride
  • DHAD
  • MITOXANTRONE
  • MITOXANTRONE DIHYDROCHLORIDE
  • MLS001333711
  • SMR000058480
  • cid_4212
  • cid_5458171
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine receptor
  • HTR6
  • Histamine H1 receptor
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
37 Ki 4 IC50
  • CAS_3575-80-2
  • MELPERONE
  • NSC_15387
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • DRD2
  • DRD3
  • HTR1A
  • HTR1B
  • HTR1D
  • HTR2A
  • HTR2C
  • HTR3A
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • adrenergic Alpha1
63 Ki 4 IC50
  • 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
  • CAS_107966
  • CHEMBL126632
  • CHEMBL8618
  • NAN-190
  • NSC_107966
  • 5-hydroxytryptamine receptor 7
  • ADRA1A
  • ADRA1B
  • ADRA2A
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • Beta-adrenergic receptor kinase 1
  • Cerebral cortex alpha adrenergic receptor
  • D(2) dopamine receptor
  • DRD1
  • Norepinephrine transporter
  • Serotonin (5-HT) receptor
  • Sodium-dependent noradrenaline transporter
  • Steroidogenic Factor 1
  • adrenergic Alpha1
  • adrenergic Alpha2
  • nuclear receptor subfamily 0 group B member 1
42 Ki 2 IC50 1 Kd
  • 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
  • 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1
  • 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride
  • 4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride
  • 4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride
  • DL-ADRENALINE HYDROCHLORIDE
  • EPINEPHRINE
  • EPINEPHRINE,(+)
  • MLS001333244
  • SMR000058236
  • cid_5924
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • Anthrax Lethal Factor (LF)
  • Bone morphogenetic protein 1
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase (2 and 3)
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 13
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase 9
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-2
  • Matrix metalloproteinase-25
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
33 Ki 138 IC50 2 Kd 1 Other
  • (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide
  • BMCL16311 Compound 1a
  • CGS 27023
  • CGS 27023A
  • CHEMBL514138
  • hydroxamate analogue 1
  • 5-HT5B
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Acetylcholinesterase
  • Bile salt export pump
  • Butyrylcholinesterase (BChE)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A
  • Cytochrome P450 1B1
  • HTR2C
  • HTR5A
  • Histamine H3 receptor
  • Melatonin
  • Melatonin 1C
  • Melatonin receptor
  • Melatonin receptor type 1C
  • Multidrug resistance-associated protein 4
  • Myeloperoxidase
  • Quinone Reductase 2 (QR2)
  • Ribosyldihydronicotinamide dehydrogenase [quinone]
  • Serotonin (5-HT) receptor
168 Ki 32 IC50 2 Kd 17 EC50
1 ΔG°
  • CHEMBL45
  • Melatonin
  • N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide