BDBM50103514 CHEBI:4975::Famotidine::Fluxid::MK-208::Pepcid::Pepcid Ac::Pepcid Rpd

SMILES NC(=N)Nc1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI Key InChIKey=XUFQPHANEAPEMJ-UHFFFAOYSA-N

Data  12 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50103514   

TargetCarbonic anhydrase 7(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  45nMAssay Description:Inhibition of recombinant human CA12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  58nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  98nMAssay Description:Inhibition of recombinant human CA6 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  126nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  172nMAssay Description:Inhibition of recombinant human CA13 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  677nMAssay Description:Inhibition of recombinant human CA14 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  922nMAssay Description:Inhibition of recombinant human CA1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  939nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  1.43E+3nMAssay Description:Inhibition of recombinant human CA5a preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi:  5.33E+3nMAssay Description:Inhibition of recombinant human CA5b preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50103514(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human CA3 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed