BDBM50277889 CARFILZOMIB::CHEMBL451887
SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1
InChI Key InChIKey=BLMPQMFVWMYDKT-NZTKNTHTSA-N
Data 47 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50277889
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Nanjing Forestry University
Curated by ChEMBL
Nanjing Forestry University
Curated by ChEMBL
Affinity DataIC50: 9.21E+4nMAssay Description:Inhibition of human ERG in HEK293 cells assessed as effect on QT intervalMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University
Curated by ChEMBL
Nanjing Forestry University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome using Suc-LLVY-AMC as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair