BDBM449100 Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- (tetrahydro-pyran-4-yl)- piperidine-4-sulfonyl]- benzylamide::US10696692, Example 224::US10696692, Example 78
SMILES O=C(NCc1ccc(cc1)S(=O)(=O)C1CCN(CC1)C1CCOCC1)c1cnc2nccn2c1
InChI Key InChIKey=CGCREZKUAIIBAE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 449100
Affinity DataIC50: 3.98nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair