BDBM449100 Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- (tetrahydro-pyran-4-yl)- piperidine-4-sulfonyl]- benzylamide::US10696692, Example 224::US10696692, Example 78

SMILES O=C(NCc1ccc(cc1)S(=O)(=O)C1CCN(CC1)C1CCOCC1)c1cnc2nccn2c1

InChI Key InChIKey=CGCREZKUAIIBAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449100   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449100(Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- ...)
Affinity DataIC50:  3.98nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449100(Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- ...)
Affinity DataIC50:  4nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent