BDBM50565310 CHEMBL4792981

SMILES C[C@@H](Nc1ccc2[nH]nc(\C=C\c3ccccn3)c2c1)c1cc(F)cc(F)c1

InChI Key InChIKey=ZHOXAGNPCZTRBN-HZRUHFOJSA-N

Data  3 IC50  20 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565310   

TargetNT-3 growth factor receptor(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565310(CHEMBL4792981)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to wild-type human partial length TRKC (Q531 to G825 residues) expressed in mammalian expression system by Kinomescan method relativ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565310(CHEMBL4792981)
Affinity DataIC50:  2nMAssay Description:Inhibition of TrkC (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed