BDBM50318300 CHEMBL1095097::EPLERENONE::SC-66110

SMILES COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]23O[C@@H]2C[C@@]2(C)[C@@H](CC[C@@]22CCC(=O)O2)[C@H]13

InChI Key InChIKey=JUKPWJGBANNWMW-VWBFHTRKSA-N

Data  4 KI  37 IC50  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50318300   

TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity to recombinant human progesterone receptor LBD by fluormone PL red-fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at progesterone receptor beta (unknown origin) by NH Pro assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at progesterone receptor beta (unknown origin) by NH Pro assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Dexamethasone from glucocorticoid receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [[3H]-Progesterone from progesterone receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]progestrone from PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed