BDBM50318300 CHEMBL1095097::EPLERENONE::SC-66110

SMILES COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]23O[C@@H]2C[C@@]2(C)[C@@H](CC[C@@]22CCC(=O)O2)[C@H]13

InChI Key InChIKey=JUKPWJGBANNWMW-VWBFHTRKSA-N

Data  4 KI  37 IC50  4 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318300   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)Copy SMILESCopy InChI

Affinity DataIC50:  135nMAssay Description:Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor act...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
KEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
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