BDBM50521571 CHEMBL4464990
SMILES Fc1cc2[C@H](CCOc2cc1S(=O)(=O)Nc1ccncn1)N1CC[C@@H](C[C@@H]1c1ccccn1)C(F)(F)F
InChI Key InChIKey=XQUOWYVEKSXNET-RYGJVYDSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50521571
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKd: 0.380nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Inhibition of full length rat Nav1.7 at -60 mV holding potential by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair