BDBM50530315 CHEMBL4520531

SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccc3ccccc3c2)cc1O

InChI Key InChIKey=HUECFCSRZKSRJF-UHFFFAOYSA-N

Data  3 KI  14 IC50  5 Kd  10 EC50

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50530315   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha V73A mutant in presence of ATP by radiometric kinase assay relative to controlMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK2alpha (unknown origin) assessed as reduction in GST-Six1 phosphorylation in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of CK2alpha (unknown origin) assessed as reduction in nucleolin phosphorylation in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay relative to controlMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha V73A mutant in presence of ATP by radiometric kinase assay relative to controlMore data for this Ligand-Target Pair
TargetCasein kinase II subunit beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK2beta autophosphorylation (unknown origin) in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK2alpha (unknown origin) assessed as reduction in GST-Six1 phosphorylation in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha H160A mutant in presence of ATP by radiometric kinase assay relative to controlMore data for this Ligand-Target Pair
TargetCasein kinase II subunit beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK2beta autophosphorylation (unknown origin) in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of CK2alpha (unknown origin) assessed as reduction in nucleolin phosphorylation in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay relative to controlMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha H160A mutant in presence of ATP by radiometric kinase assay relative to controlMore data for this Ligand-Target Pair