BDBM50530315 CHEMBL4520531

SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccc3ccccc3c2)cc1O

InChI Key InChIKey=HUECFCSRZKSRJF-UHFFFAOYSA-N

Data  3 KI  14 IC50  5 Kd  10 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50530315   

TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in p21 phosphorylation at Thr145 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 assuming basal level of non-responsive P-alpha...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 assuming basal level of non-responsive P-alpha...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as reduction in STAT3 phosphorylation at Y705 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in alpha-catenin phosphorylation at Ser641 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50530315(CHEMBL4520531)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of CK2 in human 786-0 cells assessed as decrease in p21 phosphorylation at Thr145 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair