BDBM23971 (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid::Bestatin::CHEMBL29292::Ubenimex
SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
InChI Key InChIKey=VGGGPCQERPFHOB-RDBSUJKOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 23971
Affinity DataKi: 0.5nMAssay Description:Competitive inhibition of pig APN using L-leucine-p-nitroanilide as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidneyMore data for this Ligand-Target Pair
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
University of Upper Alsace
Curated by ChEMBL
University of Upper Alsace
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of Aeromonas proteolytica leucyl aminopeptidase using L-leucine para-notroanilide as substrate assessed as release of para-nitroaniline by...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibitory activity against Leucine aminopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibitory activity against aminopeptidase BMore data for this Ligand-Target Pair
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
University of Pennsylvania
Curated by ChEMBL
University of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Competitive inhibition of bovine LAPc using L-leucine-p-nitroanilide as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
Affinity DataKi: 2.37E+3nMAssay Description:Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
Affinity DataKi: 3.03E+3nMAssay Description:Inhibition of mouse APNMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of porcine kidney APN using L-leucine para-notroanilide as substrate assessed as release of para-nitroaniline by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.73E+3nMAssay Description:Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate by Dixon methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 7.80E+3nMAssay Description:Inhibitory activity against Aminopeptidase MMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Human)
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 4.00E+5nMAssay Description:Inhibition constant (Ki) for human intestinal peptide carrierMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair