BDBM23971 (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid::Bestatin::CHEMBL29292::Ubenimex

SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O

InChI Key InChIKey=VGGGPCQERPFHOB-RDBSUJKOSA-N

Data  20 KI  120 IC50  3 Kd

PDB links: 26 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23971   

TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL

LigandBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Copy SMILESCopy InChI

Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of porcine kidney microsome APN assessed as L-Leu-p-nitroanilide hydrolysisMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL

LigandBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Copy SMILESCopy InChI

Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI