BDBM101904 CHEMBL2147972::US8530490, 176

SMILES CC(C)(NS(=O)(=O)c1ccccc1)c1ccc(Cn2ccc(=O)[nH]c2=O)cc1

InChI Key InChIKey=GCOVIPRZHPHWAC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 101904   

LigandPNGBDBM101904(CHEMBL2147972 | US8530490, 176)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM101904(CHEMBL2147972 | US8530490, 176)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of human dUTPase-mediated cell proliferation in HeLa S3 cells assessed as compound concentration required to reduce 50% of 1 uM of FdUrd T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM101904(CHEMBL2147972 | US8530490, 176)
Affinity DataIC50: 2.69E+3nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2013
Entry Details
US Patent